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Gout Medication Prevents Progression of Coronary Disease

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Colchicine usage found to reduce the risk of cardiovascular death, heart attack and stroke by almost one third, according to an Australian-Dutch trial led by Perth GenesisCare cardiologists, Professor Peter Thompson and Dr Mark Nidorf, in collaboration with the Dutch Network for Cardiovascular Research (WCN) in the Netherlands. The trial confirmed that low dose colchicine…

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Updated Guidelines Endorse Genomic Tests, Targeted Treatments for Metastatic Pancreatic Cancer

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Patients with metastatic pancreatic cancer should undergo germline and somatic testing to identify those who can benefit from targeted therapies, according to an updated guideline from the American Society of Clinical Oncology (ASCO). The 2018 ASCO guideline focused on second-line therapy for patients who had experienced progression or intolerable toxicity after first-line therapy. The updated…

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Ensartinib Bests Crizotinib in ALK+ Non-Small Cell Lung Cancer

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Ensartinib significantly prolonged progression-free survival, compared with crizotinib, in patients with ALK-positive non-small-cell lung cancer (NSCLC) in the eXalt3 study. Ensartinib, being developed by Xcovery Holdings, is a potent, next-generation, once-daily oral ALK inhibitor with broad preclinical activity against ALK-resistance mutations. “Its potency is more than 10 times greater than that of crizotinib in enzyme…

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Lung Cancer Mortality Rate: New Findings

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In the United States in recent years, mortality rates from the most common lung cancer, non-small cell lung cancer (NSCLC), have fallen sharply, due primarily to recent advances in treatment, said new study. The study was led by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health. “Reduced tobacco consumption…

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Aspirin may Hasten Progression of Cancers in Elderly Patients

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Aspirin may decrease the risk of developing cancer, according to the study conducted by a binational team led by researchers at Massachusetts General Hospital (MGH), the Berman Center in Minnesota, and Monash University in Australia. Compelling evidence from clinical trials that included predominantly middle-aged adults demonstrates that aspirin may reduce the risk of developing cancer,…

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Canakinumab Holds Potential In Treating Large Joint Osteoarthritis

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Patients receiving interleukin-1£] (IL-1£]) inhibitors had lower rates of total hip or total knee replacements over an average follow up of 3.7 years, according to an exploratory analysis of data from the CANTOS (Canakinumab Anti-inflammatory Thrombosis Outcomes Study), which is a randomized double-blind, placebo-controlled trial. These findings are important, as no treatments currently exist that…

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World Hepatitis Day

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Highlights: World Hepatitis Day is celebrated annually on 28th July to create awareness on the global burden of viral hepatitis Around 290 million people are living with viral hepatitis unaware worldwide The theme for 2020 is ‘Find The Missing Millions’. World Hepatitis Day is celebrated annually on July 28th.Organizations around the world celebrate World Hepatitis…

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EMA Green Light for Avapritinib for GIST, Acalabrutinib for CLL

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The European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP) has given a thumbs up to two new oncology drugs. The Committee has recommended granting conditional marketing authorization for avapritinib (Ayvakit, Blueprint Medicines) for use in adults with unresectable or metastatic gastrointestinal stromal tumors (GIST) harboring a platelet-derived growth factor receptor alpha (PDGFRA) exon 18 mutation,…

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Ophthalmologists Called to Catch Cancers Earlier

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Significant advances in the management of eye cancer mean that early referrals to subspecialists are crucial when ophthalmologists suspect disease in their patients, two leaders in the field say. “Don’t be afraid or embarrassed to contact an ocular oncologist,” said Carol Shields, MD, from Wills Eye Hospital in Philadelphia. Improvements in prognosis and treatment are…

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