Bosulif 100mg 28 tablet

Tablets per box:28, Manufacturer: Pfizer

Description

Composition Bosutinib
Primary Use Bosulif is indicated for adult patients with newly diagnosed chronic phase Chronic Myeloid Luekemia(CML).

Medicine Overview of Bosulif 100mg

uses

Uses of Bosulif 100mg

BOSULIF (bosutinib) is a prescription medicine used for the treatment of adult patients with:

  • Newly-diagnosed chronic phase Ph+ chronic myelogenous leukemia (CML). This indication is approved under accelerated approval based on molecular and cytogenetic response rates. Continued approval for this indication may be contingent upon verification and confirmation of clinical benefit in an ongoing long-term follow up trial.
  • Chronic, accelerated, or blast phase Ph+ CML with resistance or intolerance to prior therapy.
uses

Bosulif 100mg side effects

Common

  • The common side effects of Bosulif 100mg for those patients who are newly diagnosed include: diarrhea, nausea, low platelet counts, rash, stomach pain, and changes in liver function tests.
  • The common side effects of Bosulif 100mg for those patients who no longer benefit from or did not tolerate other treatment include: diarrhea, nausea, stomach pain, rash, low platelet counts, vomiting, low red blood cell counts, tiredness, fever, cough, headache, changes in liver function tests, and swelling.
uses

How to use Bosulif 100mg

  • Take Bosulif 100mg exactly as prescribed by your doctor.
  • Do not change your dose or stop taking Bosulif 100mg without first talking with your doctor.
  • Take Bosulif 100mg with food.
  • Swallow Bosulif 100mg tablets whole. Do not crush, break, or cut BOSULIF tablets. Do not touch or handle crushed or broken Bosulif 100mg tablets.

How Bosulif 100mg works

Bosutinib is a type of drug called a protein tyrosine kinase inhibitor (TKI). Tyrosine kinases are proteins that act as chemical messengers to stimulate cancer cells to grow. Bosutinib blocks (inhibits) a protein made by CML cells that have the Philadelphia chromosome. Blocking this protein stops the leukaemia cells growing.

In Depth Information on Bosulif 100mg

Expert advice for Bosulif 100mg

  • Cancer drugs can interact with some other medicines and herbal products. Tell your doctor or pharmacist about any medicines you are taking. This includes vitamins, herbal supplements and over the counter remedies.
  • You should not eat grapefruit or drink grapefruit juice when you are taking this drug because it can react with the drug.
  • If you take an antacid or H2 blocker medicine, take it at least 2 hours before or 2 hours after BOSULIF. If you take a Proton Pump Inhibitor (PPI) medicine, talk to your doctor or pharmacist.
  • If you miss a dose of Bosulif 100mg, take it as soon as you remember. If you miss a dose by more than 12 hours, skip that dose and take your next dose at your regular time. Do not take 2 doses at the same time.
  • If you take too much Bosulif 100mg, call your doctor or go to the nearest hospital emergency room right away.
  • Tell your doctor right away if you get respiratory tract infections, loss of appetite, headache, dizziness, back pain, joint pain, or itching while taking Bosulif 100mg. These may be symptoms of a severe allergic reaction.
  • Your doctor may change your dose, temporarily stop, or permanently stop treatment with BOSULIF if you have certain side effects.
  • BOSULIF may cause fertility problems in females and males. This may affect your ability to have a child. Talk to your doctor if this is a concern for you.

Bosulif 100mg related warnings

Special precautions for Bosulif 100mg

alcohol
Alcohol
There is no evidence of any interaction. Please consult your doctor.
pregnancy
Pregnancy
caution
Bosulif 100mg can harm your unborn baby. Tell your doctor right away if you become pregnant while taking Bosulif 100mg. Females who are able to become pregnant should have a pregnancy test before starting treatment with Bosulif 100mg and should use effective birth control (contraception) during treatment with Bosulif 100mg and for at least 1 month after the last dose. Talk to your doctor about birth control methods that may be right for you
lactation
Lactation
WEIGH RISKS VS BENEFITS
It is not known if Bosulif 100mg passes into your breast milk or if it can harm your baby. Do not breastfeed during treatment with Bosulif 100mg and for at least 1 month after the last dose
driving
Driving
There is no evidence of any interaction. Please consult your doctor.
kidney
Kidney
caution

Bosulif 100mg may cause kidney problems. Your doctor should do tests to check your kidney function when you start treatment with Bosulif 100mg and during your treatment. Call your doctor right away if you get any of the following symptoms during your treatment with Bosulif 100mg:

  • you urinate more often than normal
  • you urinate less often than normal
  • you make a much larger amount of urine than normal
  • you make a much smaller amount of urine than normal
liver
Liver
caution
Bosulif 100mg may cause liver problems. Your doctor should do blood tests to check your liver function regularly during your treatment with Bosulif 100mg. Call your doctor right away if your skin or the white part of your eyes turns yellow (jaundice) or you have dark “tea color” urine.

What if you miss a dose of Bosulif 100mg?

If you miss a dose of Bosulif 100mg, take it as soon as you remember. If you miss a dose by more than 12 hours, skip that dose and take your next dose at your regular time. Do not take 2 doses at the same time.

Additional information

Weight 0.030 kg